Tramadol-Med-Plus

TRAMADOL

Tramadol is a narcotic-like pain reliever.

Tramadol is used to treat moderate to severe pain. Tramadol extended-release is used to treat moderate to severe chronic pain when treatment is needed around the clock.

Tramadol may also be used for other purposes not listed in this medication guide.

Important information about tramadol

You should not take this medication if you are allergic to tramadol, if you have ever been addicted to drugs or alcohol, or if you have ever attempted suicide. Do not take tramadol while you are intoxicated (drunk) or taking any of the following: alcohol or street drugs, narcotic pain medicine, sedatives or tranquilizers, or medicine for depression, anxiety, or mental illness.

Seizures (convulsions) have occurred in some people taking this medicine. Tramadol may be more likely to cause a seizure if you have a history of seizures or head injury, a metabolic disorder, or if you are taking certain medicines such as antidepressants, muscle relaxers, narcotic, or medicine for nausea and vomiting.

Seek emergency medical attention if you think you have used too much of this medicine. A tramadol overdose can be fatal.

Tramadol may be habit-forming. Tell your doctor if you feel the medicine is not working as well in relieving your pain. Never share tramadol with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

Do not crush the tramadol tablet. This medicine is for oral (by mouth) use only. Powder from a crushed tablet should not be inhaled or diluted with liquid and injected into the body. Using this medicine by inhalation or injection can cause life-threatening side effects, overdose, or death.

Before taking tramadol

You should not take this medication if you are allergic to tramadol, if you have ever been addicted to drugs or alcohol, or if you have ever attempted suicide.

Do not take tramadol while you are intoxicated (drunk) or taking any of the following:

• alcohol or street drugs;
• narcotic pain medicine;
• sedatives or tranquilizers (such as Valium);
• medicine for depression or anxiety; or
• medicine for mental illness (such as bipolar disorder, schizophrenia).

Seizures have occurred in some people taking tramadol. Talk with your doctor about your seizure risk, which may be higher if you have:

• a history of drug or alcohol addiction;
• a history of epilepsy or other seizure disorder;
• a history of head injury;
• a metabolic disorder; or
• if you are also taking an antidepressant, muscle relaxer, narcotic, antipsychotic, or medicine for nausea and vomiting.

To make sure you can safely take tramadol, tell your doctor if you have any of these other conditions:

• kidney disease (or if you are on dialysis);
• cirrhosis or other liver disease;
• a stomach disorder; or
• a history of depression, mental illness, or thoughts of suicide.

FDA pregnancy category C. It is not known whether tramadol will harm an unborn baby. Tramadol may cause serious or fatal side effects in a newborn if the mother uses this medication during pregnancy or labor. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Tramadol can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are taking tramadol. Do not give this medication to anyone younger than 16 years old without the advice of a doctor.

HOW SUPPLIED

Ultram (tramadol hydrochloride) 50 mg tablet (white, film-coated capsule-shaped tablet) engraved "McNeil" on one side and "659" on the other side.

Ultram (tramadol hydrochloride) 50 mg tablet - NDC 0045-0659 bottles of 100 tablets, and packages of 100 unit doses in blister packs (10 cards of 10 tablets each).

Dispense in a tight container. Store at controlled room temperature (15o to 30oC, (59o to 86oF).

(Ortho-McNeil Pharmaceutical, 3/95, 633-19-227-1)

(95/3/3)

DRUG ABUSE AND DEPENDENCE

Although tramadol can produce drug dependence of the µ-opioid type (like codeine or dextropropoxyphene) and potentially may be abused, there has been little evidence of abuse in foreign clinical experience. In clinical trials, tramadol produced effects similar to an opioid, and at supratherapeutic doses was recognized as an opioid in subjective/behavioral studies. Tolerance development has been reported to be relatively mild and withdrawal when present, is not considered to be as severe as that produced by other opioids. Part of tramadol's activity and some extension of the duration of µ-opioid activity. Delayed µ-opioid activity is believed to reduce a drug's abuse liability.

An assay for tramadol is not included in routine urine screens for drugs of abuse.

Pain Reduction

Because of its pain-relieving properties similar to a little 'like a drug, experts say that Tramadol HCl should not be taken if you have ever been addicted to controlled substances, including drugs and alcohol. The patient takes the drug should never give it to another person, especially a history of drug abuse and alcohol. It is recommended to keep drugs in a safe, dry place where others can not.

It is known to impair thinking, discernment, or reactions to some patients. Doctors warn against driving, piloting aircraft, operating heavy machinery, or do anything that requires alertness if you are into drugs, especially if you feel the side effects set in. withdrawal symptoms are also observed in patients who took the drug in a longer period. You gradually wean the drug is recommended to avoid withdrawal symptoms such as sweating, nausea, anxiety, tremors, chills, diarrhea, trouble breathing, insomnia and hallucinations.

For these reasons, it is not tramadol without a prescription and the drug should follow the instructions carefully. It should in any case, having the recommended dose, if you think that medicine is not working. In this case, ask your doctor to increase the dosage or switch to another drug.

How Should This Medicine Be Used?

Tramadol comes as a tablet and sustained release (long-acting) tablet to take by mouth. The tablet should be taken regularly with or without food every 4-6 hours as needed. Prolonged tablets should be taken once a day. Enable extended-release tablet at about the same time of day every day, and always take with food or always take without food. Take tramadol exactly as directed. Do not exceed the dose of a single dose or take more doses per day than prescribed by your doctor. Taking more tramadol than prescribed by your doctor may cause serious or fatal side effects.

Your doctor may start with a low dose of tramadol and gradually increase the amount of medications you take, no more frequently than every three days, if you take regular tablets or every 5 days if extended-release tablets.

Swallow extended-release tablets, cut, chew, or crush. Do not snort (dust inhalation crushed tablet) or inject the dissolved extended-release tablets. Take this medicine in a way that is not recommended may cause serious side effects or death.

This medication may cause dependence. Do not take a larger dose, take it more frequently or take it for a longer period of time than prescribed by your doctor. Call your doctor if you notice that it intends to take additional medications or if you notice any unusual changes in behavior or mood.

Do not stop taking tramadol without talking to your doctor. Your doctor will probably decrease your dose gradually. If you suddenly stop taking tramadol you may experience withdrawal symptoms such as nervousness, panic, sweating, difficulty falling asleep or staying asleep, runny nose, sneezing, coughing, numbness, pain, sensation burning or tingling in hands or feet, hair standing on end, chills, nausea, uncontrollable shaking of a part of your body, diarrhea, or rarely, hallucinations (seeing things or hearing voices that not exist).

Tramadol-Med-Plus

Tramadol is a drug as a painkiller.

Tramadol is used to treat moderate to severe pain. Tramadol extended-release is used to treat chronic moderate to severe pain when treatment is needed throughout the day.

Tramadol may also be used for other purposes.